Cholesterol Research Today is a free monthly online journal that collates and summarizes the latest research about Cholesterol, including details on high cholesterol, hdl, ldl, diet, risks.

High-density lipoprotein cholesterol: an emerging target for stroke treatment.

Sanossian N, Saver JL, Navab M, Ovbiagele B

Department of Neurology, University of Southern California, Los Angeles, CA 90033, USA. sanossia@yahoo.com

BACKGROUND AND PURPOSE: This review characterizes the current state of knowledge of high-density lipoprotein (HDL) in relation to stroke. SUMMARY OF REVIEW: HDL has anti-atherosclerotic and anti-inflammatory properties and is an important component in atherosclerosis. Serum HDL-cholesterol levels are inversely related to heart disease and stroke risk. There are various established and experimental treatments which can raise serum HDL cholesterol and improve its function. CONCLUSIONS: HDL is an emerging target for atherosclerotic stroke treatment with the potential to dramatically impact the care of stroke patients.

Published 27 February 2007 in Stroke, 38(3): 1104-9.
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